3 Methylpentane 1 5 Diol
 | |
| Names | |
|---|---|
| Preferred IUPAC name 2-Methylpentane-2,4-diol | |
| Other names 2-Methyl-ii,4-pentanediol | |
| Identifiers | |
| CAS Number |
|
| 3D model (JSmol) |
|
| Abbreviations | MPD |
| ChEBI |
|
| ChEMBL |
|
| ChemSpider |
|
| ECHA InfoCard | 100.003.173 |
| PubChem CID |
|
| UNII |
|
| CompTox Dashboard (EPA) |
|
| InChI
| |
| SMILES
| |
| Properties | |
| Chemic formula | C 6 H 14 O 2 |
| Tooth mass | 118.176 chiliad·mol−1 |
| Appearance | colourless liquid |
| Smell | balmy, sweetish[1] |
| Density | 0.92 1000/mL |
| Melting point | −forty °C (−40 °F; 233 K) |
| Boiling point | 197 °C (387 °F; 470 Thousand) |
| Solubility in water | miscible[ane] |
| Vapor pressure | 0.05 mmHg (20°C)[1] |
| Hazards | |
| Flash bespeak | 98.iii °C (208.nine °F; 371.4 K)[two] |
| Explosive limits | 1.3%-7.iv%[1] |
| NIOSH (US health exposure limits): | |
| PEL (Permissible) | none[one] |
| REL (Recommended) | C 25 ppm (125 mg/miii)[1] |
| IDLH (Immediate danger) | Northward.D.[ane] |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references | |
2-Methyl-2,4-pentanediol (MPD) is an organic compound with the formula (CH3)2C(OH)CHtwoCH(OH)CHiii. This colourless liquid is a chiral diol. It is produced industrially from diacetone alcohol by hydrogenation.[three] Full European and U.s. product was 15000 tonnes in 2000.[4]
ii-Methyl-2,4-pentanediol exists equally ii enantiomers, (ivR)-(-) and (4S)-(+). In the Protein Information Depository financial institution, the iii-letter of the alphabet lawmaking "MPD" refers to the (Southward)-(-) enantiomer, while "MRD" is used to refer to the (R)-(+) version. Commercial products labeled "MPD" are usually the racemate,[five] also sold as and referred to every bit "hexylene glycol".[half dozen] [7]
Uses [edit]
ii-Methyl-2,4-pentanediol exhibits both surfactant and emulsion-stabilizing properties. Its relatively high viscosity and depression volatility are advantageous in coatings, cleansers, cosmetics, solvents, and hydraulic fluids.[eight] Although it is an irritant at college concentrations, it is sometimes used in pare care, hair intendance, soap, and eye corrective products at concentrations ranging from 0.one% - 25%.[9] [10]
It is biodegradable and unlikely to accumulate in the environs.[11]
Laboratory uses [edit]
In the laboratory information technology is a common precipitant and cryoprotectant in protein crystallography.[12] Since hexylene glycol is uniform with polar and nonpolar molecules, it competes with the solvent in a crystallography experiment causing the protein to precipitate.[13] Hexylene glycol is so effective in protein crystallography because its amphiphilic nature and small-scale, flexible structure allows it to bind to many different locations on a protein secondary structure including alpha helices and beta sheets.[14] When hexylene glycol binds to these different locations, water is removed and the poly peptide crystals anneal, which prevents ice germination during cryocrystallography techniques.[xv] Incorporation of hexylene glycol into solution has been known to improve the resolution of X-ray diffraction making protein structures easily identifiable.[xvi] Additionally hexylene glycol is not a strong denaturing agent and thus does not significantly change the structure of a protein during the crystallography procedure.[xiv]
Like related diols, information technology forms borate esters.
References [edit]
- ^ a b c d due east f grand NIOSH Pocket Guide to Chemical Hazards. "#0328". National Institute for Occupational Condom and Health (NIOSH).
- ^ CDC - NIOSH Pocket Guide to Chemical Hazards
- ^ Stylianos Sifniades, Alan B. Levy, "Acetone" in Ullmann's Encyclopedia of Industrial Chemical science, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a01_079.pub3
- ^ SIDS Initial Assessment Report for SIAM 13: Hexylene Glycol
- ^ MPD at Hampton Research , MPD Production Folio
- ^ Hexylene Glycol at Sigma Aldrich , Hexylene Glycol Product Page
- ^ Hexylene Glycol at Jena Bioscience, Hexylene Glycol Product Page
- ^ Chemicalland21.com Hexylene glycol
- ^ Kinnunen, T. (1991). "Antibacterial and antifungal properties of propylene glycol, and 1,iii-butylene glycol in vitro". Acta Dermato-Venereologica.
- ^ R. Rietschel; J. Fowler; A. Fisher Hexylene Glycol. In Fisher'south Contact Dermatitis; Holmes, Grand., Ed.; BC Decker Inc.: Hamilton,Ontario, 2008; pp 290
- ^ Rhodia Hexylene glycol GPS Condom Summary. 2012.
- ^ Crystallization Techniques: Additives, Enrico Stura, University of Glasgow
- ^ Dumetz, A. (2009). "Comparative Effects of Common salt, Organic and Polymer Precipitants on Protein Phase Behavior and Implications for Vapor Improvidence". J. Cryst. Growth. 9 (2): 682–691. doi:10.1021/cg700956b.
- ^ a b Anand, K (2002). "An overview on 2-methyl-ii,four-pentanediol in crystallization and in crystals of biological macromolecules". Acta Crystallogr. 58 (10): 1722–1728. doi:ten.1107/s0907444902014610. PMC7161645. PMID 12351894.
- ^ Viatcheslav, Berejnov (2006). "Thornea Effects of cryoprotectant concentration and cooling rate on vitrification of aqueous solutions". J. Appl. Crystallogr.
- ^ Vera, L (2006). "Strategies for Protein Crystallography". Cryst. Growth Des.
3 Methylpentane 1 5 Diol,
Source: https://en.wikipedia.org/wiki/2-Methyl-2,4-pentanediol
Posted by: ackermanpubleausing1955.blogspot.com
0 Response to "3 Methylpentane 1 5 Diol"
Post a Comment